St John’s Wort
plant
taxonomy
parts used
application
mode of action
St John’s Wort
Hypericum perforatum
Whole plant
Antidepressant and aid in sleeplessness
Used for treating many disorders including sleep disturbances. Active compounds are hyperforin and hypericin; hypericin exerts its effects via monoamine oxidase inhibition, whereas hyperforin acts via the inhibition of GABA, serotonin, dopamine, L-glutamate, and norepinephrine reuptake.